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If you could use your own blood to smooth wrinkles, fade scars, and restore youthful skin, would you?
That is exactly what platelet-rich fibrin (PRF) makes possible. This advanced regenerative treatment taps into your body’s own healing system to naturally refresh your appearance.
In this blog, you will learn how PRF works, what to expect during treatment, and why it is a key part of regenerative aesthetics.
We offer platelet-rich fibrin skin rejuvenation at our Superstition Springs location in Mesa, AZ.
Table of Contents
- What Is Platelet-Rich Fibrin (PRF)?
- What To Expect During a PRF Skin Treatment
- Who Is a Good Candidate for PRF?
- PRF vs PRP: What’s the Difference?
- Regenerative Aesthetics with Dr. Boyse at AZ Max
PRF uses your own blood to naturally rejuvenate skin by boosting collagen, improving texture, and accelerating healing, making it a top choice in regenerative aesthetics.
What Is Platelet-Rich Fibrin (PRF)?
PRF is a natural substance derived from your own blood that promotes healing and tissue regeneration.
It contains a concentrated mix of platelets, white blood cells, fibrin, and growth factors. These blood components signal your body to repair tissue, grow new cells, and boost collagen production, all essential for smoother skin and long-lasting results.
Unlike platelet-rich plasma (PRP), PRF is spun at a slower speed during processing. This method preserves stem cells, healing cells, and the fibrin architecture, resulting in a strong fibrin matrix that supports the sustained release of growth factors over time.
How PRF Supports Regenerative Aesthetics
PRF fits perfectly into the field of regenerative aesthetics by stimulating natural healing processes without synthetic additives or chemicals.
Benefits of PRF for skin rejuvenation include:
- Improved skin tone and texture means PRF boosts collagen and elastin production for better skin quality.
- Reduced fine lines and wrinkles happen as PRF plumps and strengthens sagging skin.
- Faster wound healing makes PRF ideal for post-laser treatments or microneedling.
- Natural results occur because there is no risk of allergic reaction, since it comes from your own body.
- Long-lasting effect is possible because the gradual release of growth factors leads to progressive and visible improvement.
The regenerative properties of PRF also make it suitable for treating acne scars, dark circles, and even promoting hair growth in cases of hair loss.
Learn more about Platelet-Rich Fibrin Skin Rejuventation
What To Expect During a PRF Skin Treatment
The process is simple, safe, and takes less than an hour. Here is what a typical PRF appointment looks like when performed AZ Max:
- Blood draw: A small blood sample is taken, just like during a routine lab test.
- Centrifuge spin: The blood is spun to isolate the platelet-rich layer, concentrating platelets and preserving beneficial components.
- Application or injection: The PRF is either microneedled into the skin or injected into specific areas such as under the eyes or around the mouth.
- Healing phase: Over the next few weeks, your skin begins regenerating from within.
You may see some initial swelling or redness, but there is minimal downtime. Most patients return to normal activities quickly, with full skin recovery occurring over several weeks. Results continue to build as growth factors activate collagen and tissue repair.
Who Is a Good Candidate for PRF?
Platelet-rich fibrin treatments are safe for most healthy adults who want to refresh their appearance using the body’s natural healing properties.
You may benefit from PRF if you:
- Have early signs of aging like fine lines, dull skin, or mild laxity
- Want to enhance recovery times after microneedling, laser treatments, or bone graft
- Prefer regenerative treatments over synthetic dermal filler or invasive procedures
- Struggle with under-eye dark circles, skin texture issues, or hair thinning
Since PRF uses your own blood, there is no risk of allergic reaction. Still, your medical history will be reviewed to ensure the treatment is right for you.
PRF vs PRP: What’s the Difference?
Both platelet-rich plasma (PRP) and PRF use concentrated platelets to trigger healing. However, PRF stands out for several reasons:
- No additives: PRF is 100% natural, no anticoagulants or synthetic agents
- Sustained release: PRF’s fibrin matrix supports the gradual release of growth factors over 7–10 days
- Higher healing potential: PRF retains more white blood cells and stem cells for enhanced tissue regeneration
The result is a more powerful, longer-lasting treatment with fewer complications.
Regenerative Aesthetics with Dr. Boyse at AZ Max
Dr. Brent Boyse brings his surgical expertise to the field of regenerative aesthetics. With years of experience in wound healing, tissue regeneration, and facial reconstruction, Dr. Boyse understands how to use platelet-rich fibrin (PRF) to support natural, long-lasting skin renewal.
PRF therapy is part of our regenerative aesthetics program and offers patients a way to restore smoother, healthier skin without synthetic fillers or invasive procedures. Dr. Boyse’s precision techniques, refined through performing complex surgeries like facial trauma repair and bone grafting, allow him to deliver results that look natural and promote deep healing from within.
Book a Consultation Today
PRF is one of the safest and most natural ways to restore your skin. It improves skin texture, tone, and elasticity using the healing power of your blood components. There is no filler, no chemicals, just real, long-lasting results.
If you are looking for a non-surgical option to rejuvenate your face, stimulate collagen production, or address issues like hair loss, acne scars, or dark circles, platelet-rich fibrin therapy may be exactly what you need.
To schedule a consultation at one of our 5 locations, call (480) 830-5866 or complete the online inquiry form. We have locations in Mesa, North Mesa, Queen Creek, Tempe or Show Low.
