Procedures
Platelet-Rich Fibrin Skin Rejuvenation
Platelet-Rich Fibrin Skin Rejuvenation in Mesa, AZ
Are you looking for a natural way to refresh and renew your skin?
Platelet-rich fibrin (PRF) skin rejuvenation uses your body’s own regenerative cells to improve tone, texture, and elasticity. This advanced treatment is often considered a next-generation alternative to platelet-rich plasma (PRP).
PRF delivers longer-lasting results thanks to its high concentration of white blood cells and stem cells. It gradually releases growth factors, supporting collagen production and tissue repair for smoother, healthier-looking skin.
We offer platelet-rich fibrin skin rejuvenation at our Superstition Springs location in Mesa, AZ.
Quick Overview
Platelet-rich fibrin (PRF) is a natural regenerative treatment made from your own blood, containing platelets, white blood cells, stem cells, and a fibrin matrix to promote healing and collagen production.
Injected into targeted areas or combined with microneedling, PRF helps improve skin tone, texture, elasticity, fine lines, wrinkles, acne scars, and under-eye circles. Compared to PRP, PRF delivers a higher concentration of healing components and releases growth factors gradually for longer-lasting results.
Most patients benefit from a series of 2 to 3 sessions spaced several weeks apart, with results that can last up to one year. Downtime is minimal, with simple aftercare recommendations such as avoiding strenuous activity, sun exposure, and alcohol for the first 24 to 48 hours.
What Is Platelet-Rich Fibrin (PRF)?
Platelet-rich fibrin (PRF) is a second-generation regenerative therapy made from your own blood.
PRF is derived from a simple blood draw. After processing the blood in a centrifuge, the resulting PRF matrix contains a concentrated blend of platelets, white blood cells, fibrin, circulating stem cells, and growth factors.
This injectable form is then applied directly into areas of concern to promote healing and stimulate collagen production.
Unlike PRP, which releases growth factors quickly, PRF offers a slower release of healing factors over time, allowing for sustained rejuvenation and natural-looking improvements.
What Can PRF Skin Rejuvenation Treat?
PRF injections can improve a wide range of skin conditions.
This treatment is especially effective for:
- Fine lines and wrinkles
- Skin laxity and sagging
- Uneven skin tone and texture
- Acne scars and other superficial scarring
- Dark circles and volume loss under the eyes
- Enlarged pores
- Dull or aging skin
When combined with microneedling, often referred to as a vampire facial, PRF treatment can enhance results by improving absorption and stimulating deeper collagen remodeling.
PRF vs PRP: What’s the Difference?
PRF offers a more advanced and longer-lasting alternative to PRP. While both treatments use blood components for skin rejuvenation, PRF differs from PRP in several key ways:
- No anticoagulants. PRF is 100% natural, processed without additives or anticoagulants.
- Higher concentration of platelets and white blood cells.
- Slower release of growth factors, providing more sustained benefits.
- Fibrin matrix that acts as a scaffold for cell regeneration and collagen synthesis.
These differences contribute to longer-lasting results and improved clinical outcomes compared to traditional PRP.
The PRF Skin Rejuvenation Procedure
PRF involves a simple in-office process that uses your own blood to stimulate skin renewal.
Here is what you can expect:
- Simple blood draw: A small amount of your blood is collected in-office.
- Centrifugation: The blood is spun at a low speed to separate out the PRF matrix.
- Injection: The PRF is carefully injected into targeted areas of the face, such as under the eyes, around the mouth, or into acne scars.
Optional microneedling: In some cases, PRF is combined with microneedling to create controlled micro-injuries and deliver PRF deeper into the skin.
PRF Aftercare
To support the best outcome, we recommend that you:
- Avoid strenuous activities for 24 hours.
- Refrain from direct sun exposure, heat, or alcohol for the first 48 hours.
- Keep the skin clean and hydrated with gentle, non-active skincare products.
- Avoid makeup for 24 hours after microneedling with PRF.
- Sleep on your back to avoid pressure on treated areas.
Following all post-care instructions can enhance your results and reduce the risk of irritation.
When Will I See Results?
Results develop gradually as your body responds to the healing signals from PRF. Some patients notice a subtle improvement within the first week. However, the most visible changes typically appear 4 to 6 weeks after treatment as collagen production increases.
Most patients need a series of 2 to 3 treatments spaced 4 to 6 weeks apart to achieve their best outcome, followed by occasional maintenance sessions as needed.
Results continue to improve for several months and can last up to one year with proper maintenance.
Benefits of PRF Injections for Facial Rejuvenation
PRF works with your body’s natural healing processes to deliver gradual, noticeable improvements.
- Promotes natural collagen synthesis and skin renewal
- Improves skin quality, texture, and elasticity
- Brightens the under-eye area and softens dark circles
- Reduces visible signs of aging without synthetic fillers
- Stimulates the body’s own wound healing and tissue regeneration
- Minimal downtime and faster recovery times compared to traditional treatments
Am I a Good Candidate?
Most healthy adults are candidates for PRF skin rejuvenation. This treatment is a good fit for patients who:
- Want to improve fine lines, wrinkles, or skin laxity
- Have acne scars or uneven skin texture
- Struggle with dark circles or under-eye hollowing
- Prefer a natural alternative to synthetic fillers
- Are looking for gradual, long-lasting skin improvement
Because PRF is made from your own blood, the risk of allergic reactions or complications is very low. However, patients with chronic illnesses, blood disorders, or those taking blood thinners may not be ideal candidates.
Dr. Boyse will review your full medical history and treatment goals during your consultation to determine if PRF is right for you.
Frequently Asked Questions
Yes. PRF injections are clinically backed and widely used for skin and hair rejuvenation. They stimulate natural healing, promote collagen production, and improve overall tissue quality with long-lasting results.
Most patients benefit from a series of 2 to 3 sessions spaced 4 to 6 weeks apart, followed by maintenance treatments every 6 to 12 months.
There may be mild redness, bruising, or swelling at the injection sites for 1 to 3 days. Most patients resume normal activities the next day, avoiding strenuous activities for 24 hours.
Yes. PRF can be paired with microneedling, laser treatments, or even dermal fillers to enhance facial rejuvenation results.
Results vary by individual. Many patients experience long-lasting results from the sustained release of growth factors. Collagen production also continues to improve the skin’s appearance over time.
Yes, PRF injections under eyes are a popular treatment for dark circles and volume loss. The growth factors and stem cells in PRF stimulate collagen production, brighten the under-eye area, and improve skin texture for a more youthful appearance.
Yes, PRF is often used to support natural hair growth. It helps repair hair follicles, improve scalp circulation, and stimulate stem cells. This leads to increased hair density and stronger, healthier regrowth over time. It is also a key part of our Non-Surgical Hair Loss PRF Stem Cell treatment offered at AZ Max.
PRF can support long-term hair growth, but results are not always permanent. Many patients require maintenance treatments to sustain improved hair density and scalp health over time.
Experience the Rejuvenating Power of PRF
If you are looking for a gentle, natural approach to improve your skin without synthetic products, platelet-rich fibrin treatment may be the perfect choice.
At AZ Oral & Maxillofacial Surgeons, we offer advanced PRF skin rejuvenation treatments in a safe and supportive setting. Our team will evaluate your goals and design a customized plan that fits your needs.
Schedule your consultation today with Dr. Brent Boyse at our Superstition Springs location in Mesa, AZ to discover the benefits of injectable platelet-rich fibrin. To book an appointment, call (480) 830-5866 or complete the online booking form.
